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Dog reacts to Toxic Drugs

Could your best friend be a future biter? A medical condition can cause unprovoked aggression in herding dogs and a simple test can change the path your dog may be on.

Many herding dog breeds are afflicted with a mutation of the multi-drug resistance (MDR1) gene. This gene encodes a protein (P-glycoprotein) that is responsible for removing certain drugs and toxins from the brain. Dogs that carry the MDR1 genetic defect cannot rid their brains of the problem drugs. The result is a neurotoxic buildup that can cause abnormal neurological symptoms and/or death. Read more:

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